XPNPEP3 Rabbit Polyclonal Antibody

CAT#: TA321891

Anti-XPNPEP3 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: MCF7 and A431 cells
  IHC: 25-100
  Positive control: Human lymphoma
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 34-49 amino acids of human X-prolyl aminopeptidase (aminopeptidase P) 3, putative
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 57 kDa
• Gene Name: X-prolyl aminopeptidase 3, mitochondrial
• Database Link:
  NP_071381
  Entrez Gene 321003 MouseEntrez Gene 685823 RatEntrez Gene 63929 Human
  UniProt ID Q9NQH7
• Background: The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor; and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells; and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene; however; expression of some of these isoforms in vivo is not known.
• Synonyms: APP3; ICP55; NPHPL1

Reference Data

• Protein Families: Druggable Genome, Protease