MAP1LC3A Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA, IHC |
Recommended Dilution | IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 1-120 amino acids of human microtubule-associated protein 1 light chain 3 alpha |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | microtubule associated protein 1 light chain 3 alpha |
Database Link | |
Background | MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines; suggesting that may be involved in carcinogenesis. |
Synonyms | ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3 |
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