Mitofusin 1 (MFN1) Rabbit Polyclonal Antibody

CAT#: TA321923

Anti-MFN1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 630-741 amino acids of human mitofusin 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mitofusin 1
• Database Link:
  NP_284941
  Entrez Gene 67414 MouseEntrez Gene 192647 RatEntrez Gene 55669 Human
  UniProt ID Q8IWA4
• Background: The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. Essential transmembrane GTPase; which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology; which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks
• Synonyms: hfzo1; hfzo2