IL23 Receptor (IL23R) Rabbit Polyclonal Antibody

CAT#: TA321935

Anti-IL23R Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Human sigmoid tissue Primary antibody: TA321935 (IL23R Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds

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  Immunohistochemistry of paraffin-embedded Human rectal cancer tissue using TA321935 (IL23R Antibody) at dilution 1/10 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human rectal cancer tissue using TA321935 (IL23R Antibody) at dilution 1/10, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human sigmoid tissue
  IHC: 5-20
  Positive control: Human rectal cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 31-227 amino acids of Human Interleukin-23 receptor
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 72 kDa
• Gene Name: interleukin 23 receptor
• Database Link:
  NP_653302
  Entrez Gene 209590 MouseEntrez Gene 689932 RatEntrez Gene 149233 Human
  UniProt ID Q5VWK5
• Background: The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1; and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2); and also binds to transcription activator STAT3 in a ligand-dependent manner.
• Synonyms: interleukin 23 receptor; OTTHUMP00000010660

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway