CCKBR Rabbit Polyclonal Antibody

CAT#: TA321943

Anti-CCKBR Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human stomach cancer tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 39-53 amino acids of Human cholecystokinin B receptor
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 49 kDa
• Gene Name: cholecystokinin B receptor
• Database Link:
  NP_795344
  Entrez Gene 12426 MouseEntrez Gene 25706 RatEntrez Gene 887 Human
  UniProt ID P32239
• Background: This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK); regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor; which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
• Synonyms: CCK-B; CCK2R; GASR

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction