Aquaporin 1 (AQP1) Rabbit Polyclonal Antibody

CAT#: TA321947

Anti-AQP1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human esophagus cancer
  Predicted cell location: Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 255-269 amino acids of Human aquaporin 1 (Colton blood group)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: aquaporin 1 (Colton blood group)
• Database Link:
  NP_000376
  Entrez Gene 11826 MouseEntrez Gene 25240 RatEntrez Gene 358 Human
  UniProt ID P29972
• Background: Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene.
• Synonyms: 28-kDa; 28kDa; AQP-CHIP; aquaporin 1; aquaporin 1 (channel-forming integral protein; aquaporin 1 (Colton blood group); channel-like integral membrane protein; CHIP28; CO; CO blood group); Colton blood group; MGC26324

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane