FATP1 (SLC27A1) Rabbit Polyclonal Antibody

CAT#: TA321973

Anti-SLC27A1 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 50-200
Positive control: Human esophagus cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 630-646 amino acids of human solute carrier family 27 (fatty acid transporter), member 1
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name solute carrier family 27 member 1
Background The protein involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes; but not myocytes; insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane; paralleled by increased LFCA uptake. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids .Highest levels of expression are detected in muscle and adipose tissue small; intermediate levels in small intestine; and barely detectable in liver.
Synonyms ACSVL5; FATP; FATP-1; FATP1
Reference Data
Protein Families Transmembrane
Protein Pathways PPAR signaling pathway

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