FLT4 Rabbit Polyclonal Antibody

CAT#: TA321983

Anti-FLT4 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IF
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 62-75 amino acids of human fms-related tyrosine kinase 4
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: fms related tyrosine kinase 4
• Database Link:
  NP_002011
  Entrez Gene 14257 MouseEntrez Gene 114110 RatEntrez Gene 2324 Human
  UniProt ID P35916
• Background: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD; and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation; survival and migration of endothelial cells; and regulates angiogenic sprouting.
• Synonyms: FLT-4; FLT41; LMPH1A; PCL; VEGFR-3; VEGFR3

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Focal adhesion