ENPP6 Rabbit Polyclonal Antibody

CAT#: TA322012

Anti-ENPP6 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA322012 (ENPP6 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA322012 (ENPP6 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 10-50
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm, Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 119-419 amino acids of human ectonucleotide pyrophosphatase/phosphodiesterase 6
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ectonucleotide pyrophosphatase/phosphodiesterase 6
• Database Link:
  NP_699174
  Entrez Gene 306460 RatEntrez Gene 320981 MouseEntrez Gene 133121 Human
  UniProt ID Q6UWR7
• Background: Choline-specific glycerophosphodiester phosphodiesterase. Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid; showing it has a lysophospholipase C activity. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C; p-nitrophenyl phosphorylcholine in vitro; while it does not hydrolyze the classical nucleotide phosphodiesterase substrate; p-nitrophenyl thymidine 5'-monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine; phosphatidylinositol; phosphatidylserine; phosphatidylglycerol and phosphatidic acid.
• Synonyms: NPP6

Reference Data

• Protein Families: Secreted Protein
• Protein Pathways: Ether lipid metabolism