SLC22A6 Rabbit Polyclonal Antibody

CAT#: TA322015

Anti-SLC22A6 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: Human fetal kidney tissue Primary antibody: TA322015 (SLC22A6 Antibody) at dilution 1/900 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 3 minutes

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA322015 (SLC22A6 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA322015 (SLC22A6 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Human fetal kidney tissue
  IHC: 50-200
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 551-563 amino acids of Human solute carrier family 22 (organic anion transporter), member 6
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 56 kDa
• Gene Name: solute carrier family 22 member 6
• Database Link:
  NP_695009
  Entrez Gene 18399 MouseEntrez Gene 29509 RatEntrez Gene 9356 Human
  UniProt ID Q4U2R8
• Background: The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions; some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate; ketoglutarate; etc). Mediates the sodium-independent uptake of 2;3-dimercapto-1-propanesulfonic acid (DMPS) By similarity.
• Synonyms: HOAT1; OAT1; PAHT; ROAT1

Reference Data

• Protein Families: Transmembrane