COX6B2 Rabbit Polyclonal Antibody

CAT#: TA322050

Anti-COX6B2 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: A549 cells, Primary antibody: COX6B2 Antibody at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds

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  The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using COX6B2 Antibody at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)

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  The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using COX6B2 Antibody at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:1000-5000, WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 1-89 amino acids of human cytochrome c oxidase subunit VIb polypeptide 2 (testis)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 11 kDa
• Gene Name: cytochrome c oxidase subunit 6B2
• Database Link:
  NP_653214
  Entrez Gene 333182 MouseEntrez Gene 654441 RatEntrez Gene 125965 Human
  UniProt ID Q6YFQ2
• Background: Cytochrome c oxidase is the terminal enzyme of the electron transfer chain in aerobic bacteria as well as in the mitochondria of plants and animals. Bacterial cytochrome c oxidases are composed of three different subunits and include two hemes a and two copper atoms as prosthetic groups. The enzyme from eukaryotes is more complex and includes three subunits encoded on mitochondrial DNA; which are the homologues of the subunits of the bacterial enzyme; and in addition contains a number of subunits encoded in the nucleus. It is generally agreed that the mitochondrially coded subunits with their associated prosthetic groups are the functional core of the enzyme. The role of the nuclear coded subunits in cytochrome c oxidase function remains a matter of conjecture. cytochrome c oxidase subunit VIb polypeptide 2 Connects the two COX monomers into the physiological dimeric form.
• Synonyms: COXVIB2; CT59

Reference Data

• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease