SP1 Rabbit Polyclonal Antibody

CAT#: TA322074

Anti-SP1 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 50-200
Positive control: Human colon cancer
Predicted cell location: Cytoplasm, Nucleus
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 609-622 amino acids of human Sp1 transcription factor
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name Sp1 transcription factor
Background The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes; including cell differentiation; cell growth; apoptosis; immune responses; response to DNA damage; and chromatin remodeling. Post-translational modifications such as phosphorylation; acetylation; glycosylation; and proteolytic processing significantly affect the activity of this protein; which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms Sp1 transcription factor; specificity protein 1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
Protein Pathways Huntington's disease, TGF-beta signaling pathway

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