RAD52 Rabbit Polyclonal Antibody

CAT#: TA322080

Anti-RAD52 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: K562, PC3 and SKOV3 cell lysates
  IHC: 30-150
  Positive control: Human lung cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 360-375 amino acids of Human RAD52 homolog (S. cerevisiae)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: RAD52 homolog, DNA repair protein
• Database Link:
  NP_602296
  Entrez Gene 19365 MouseEntrez Gene 297561 RatEntrez Gene 5893 Human
  UniProt ID P43351
• Background: The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52; a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends; and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51; which suggested its role in RAD51 related DNA recombination and repair.
• Synonyms: RP11-359B12.2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Homologous recombination