ACAD11 Rabbit Polyclonal Antibody

CAT#: TA322145

Anti-ACAD11 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal liver tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 121-400 amino acids of human acyl-CoA dehydrogenase family, member 11
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 87 kDa
• Gene Name: acyl-CoA dehydrogenase family member 11
• Database Link:
  NP_115545
  Entrez Gene 102632 MouseEntrez Gene 315973 RatEntrez Gene 84129 Human
  UniProt ID Q709F0
• Background: The deduced full-length?ACAD11?protein contains an N-terminal aminoglycoside phosphotransferase domain; followed by a mitochondria localization signal and ACAD N-terminal; middle; and C-terminal domains. It also has a glycosylation site and a C-terminal peroxisome-targeting signal. The ACAD domain contains a catalytic aspartate rather than the catalytic glutamate found in most other ACADs. Real-time RT-PCR detected variable?ACAD11?expression in all tissues examined; with highest expression in adult brain; followed by heart; liver; spinal cord; and kidney. Western blot analysis of fractionated human cerebellum and kidney revealed thatACAD11?associated with mitochondrial membranes; but not mitochondrial matrix. Immunohistochemical analysis showed that?ACAD11colocalized with a mitochondrial marker in human neuroblastoma cells.
• Synonyms: ACAD-11

Reference Data

• Protein Families: Druggable Genome