Cyclin B1 (CCNB1) Rabbit Polyclonal Antibody

CAT#: TA322151

Anti-CCNB1 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA322151 (CCNB1 Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA322151 (CCNB1 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 61-74 amino acids of Human cyclin B1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cyclin B1
• Database Link:
  NP_114172
  Entrez Gene 25203 RatEntrez Gene 268697 MouseEntrez Gene 891 Human
  UniProt ID P14635
• Background: G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene. The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found; a constitutively expressed transcript and a cell cycle-regulated transcript; that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
• Synonyms: CCNB

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Cell cycle, Oocyte meiosis, p53 signaling pathway, Progesterone-mediated oocyte maturation