FOXL2 Rabbit Polyclonal Antibody

CAT#: TA322192

Anti-FOXL2 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 500-2000
WB positive control: Mouse brain and heart tissue
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 364-376 amino acids of Human forkhead box L2
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 50 kDa
Gene Name forkhead box L2
Background This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Critical factor essential for ovary differentiation and maintenance; and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Synonyms BPES; BPES1; PFRK; PINTO; POF3
Reference Data
Protein Families Druggable Genome, Transcription Factors

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