Livin (BIRC7) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommended Dilution | WB: 500-2000 WB positive control: Mouse adrenal gland tissue lysate IHC: 50-200 Positive control: Human gastric cancer Predicted cell location: Cytoplasm and Nucleus |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Full length fusion protein |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 33 kDa |
Gene Name | baculoviral IAP repeat containing 7 |
Database Link | |
Background | The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases; while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties; with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.? |
Synonyms | KIAP; LIVIN; ML-IAP; MLIAP; RNF50 |
Reference Data | |
Protein Families | Druggable Genome |
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