Ceramide synthase 2 (CERS2) Rabbit Polyclonal Antibody

CAT#: TA322212

Anti-CERS2 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Mouse skin tissue lysate Primary antibody: TA322212 (CERS2 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 90 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA322212 (CERS2 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA322212 (CERS2 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse skin tissue lysate
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 100-114 amino acids of human ceramide synthase 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: ceramide synthase 2
• Database Link:
  NP_071358
  Entrez Gene 76893 MouseEntrez Gene 310667 RatEntrez Gene 29956 Human
  UniProt ID Q96G23
• Background: This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis. Expressed in kidney; liver; brain; heart; placenta and lung.
• Synonyms: L3; LASS2; SP260; TMSG1

Reference Data

• Protein Families: Transcription Factors, Transmembrane