Secretin (SCT) Rabbit Polyclonal Antibody

CAT#: TA322215

Anti-SCT Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 34-49 amino acids of human secretin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: secretin
• Database Link:
  NP_068739
  Entrez Gene 20287 MouseEntrez Gene 24769 RatEntrez Gene 6343 Human
  UniProt ID P09683
• Background: Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach; small intestine; and pancreas. Secretin deficiency has been implicated in autistic syndrome; suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.
• Synonyms: secretin

Reference Data

• Protein Families: Druggable Genome, Secreted Protein