VANGL2 Rabbit Polyclonal Antibody

CAT#: TA322268

Anti-VANGL2 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 200-1000
WB positive control: NIH/3T3 cells
IHC: 15-50
Positive control: Human lung cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 20-34 amino acids of human vang-like 2 (van gogh, Drosophila)
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 60 kDa
Gene Name VANGL planar cell polarity protein 2
Background The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity; especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. Plays a role in the regulation of planar cell polarity; particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.
Synonyms LPP1; LTAP; STB1; STBM; STBM1
Reference Data
Protein Families Transmembrane
Protein Pathways Wnt signaling pathway

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