LRIG1 Rabbit Polyclonal Antibody

CAT#: TA322346

Anti-LRIG1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm, Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1073-1085 amino acids of Human leucine-rich repeats and immunoglobulin-like domains 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: leucine-rich repeats and immunoglobulin like domains 1
• Database Link:
  NP_056356
  Entrez Gene 16206 MouseEntrez Gene 312574 RatEntrez Gene 26018 Human
  UniProt ID Q96JA1
• Background: Leucine-rich repeats and immunoglobulin-like domains protein 1?is a?protein?that in humans is encoded by the?LRIG1?gene.?It encodes a?transmembrane protein?that has been shown to interact with receptor tyrosine kinases of the?EGFR-family?;?MET?and?RET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases; through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
• Synonyms: LIG-1; LIG1

Reference Data

• Protein Families: Transmembrane