ADAM28 Rabbit Polyclonal Antibody

CAT#: TA322387

Anti-ADAM28 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm, Secreted
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 40-54 amino acids of human ADAM metallopeptidase domain 28
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ADAM metallopeptidase domain 28
• Database Link:
  NP_055080
  Entrez Gene 13522 MouseEntrez Gene 290344 RatEntrez Gene 10863 Human
  UniProt ID Q9UKQ2
• Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins; and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions; including fertilization; muscle development; and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform; while the longer version encodes a transmembrane isoform.
• Synonyms: ADAM 28; eMDC II; eMDCII; MDC-L; MDCL

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane