NFKBIL2 (TONSL) Rabbit Polyclonal Antibody
Other products for "TONSL"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 500-2000 WB positive control: Mouse brain tissue lysate IHC: 50-200 Positive control: Human prostate cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to C terminal 250 amino acids of human tonsoku-like, DNA repair protein |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | tonsoku-like, DNA repair protein |
Database Link | |
Background | The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.? |
Synonyms | IKBR; NFKBIL2 |
Reference Data | |
Protein Families | Transcription Factors |
Documents
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in shipping.