ATG4B Rabbit Polyclonal Antibody

CAT#: TA322400

Anti-APG4B Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Hela cells Primary antibody: TA322400 (ATG4B Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 5-20 amino acids of Human Autophagy-related protein 4 homolog B
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: autophagy related 4B cysteine peptidase
• Database Link:
  NP_037457
  Entrez Gene 66615 MouseEntrez Gene 316640 RatEntrez Gene 23192 Human
  UniProt ID Q9Y4P1
• Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation; metamorphosis; non-apoptotic cell death; and aging. Reduced levels of autophagy have been described in some malignant tumors; and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
• Synonyms: APG4B; AUTL1

Reference Data

• Protein Families: Protease
• Protein Pathways: Regulation of autophagy