14 3 3 gamma (YWHAG) Rabbit Polyclonal Antibody

CAT#: TA322404

Anti-YWHAG Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 1000-5000
WB positive control: 293T and Jurkat cells
IHC: 50-200
Positive control: Human lung cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 141-154 amino acids of Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 28 kDa
Gene Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
Background This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals; and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells; and is also highly expressed in skeletal and heart muscles; suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C; proteins involved in various signal transduction pathways.
Synonyms 14-3-3GAMMA; PPP1R170
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

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