14 3 3 gamma (YWHAG) Rabbit Polyclonal Antibody

CAT#: TA322405

Anti-YWHAG Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-3: Hela cells 293T cells Jurkat cells Primary antibody: TA322405 (YWHAG Antibody) at dilution 1/1800 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA322405 (YWHAG Antibody) at dilution 1/100 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA322405 (YWHAG Antibody) at dilution 1/100, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Hela, 293T and Jurkat cells
  IHC: 50-200
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 141-154 amino acids of Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 28 kDa
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Database Link:
  NP_036611
  Entrez Gene 22628 MouseEntrez Gene 56010 RatEntrez Gene 7532 Human
  UniProt ID P61981
• Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals; and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells; and is also highly expressed in skeletal and heart muscles; suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C; proteins involved in various signal transduction pathways.
• Synonyms: 14-3-3GAMMA; PPP1R170

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis