PDCD10 Rabbit Polyclonal Antibody

CAT#: TA322435

Anti-PDCD10 Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 50 μg Lane 1-3: Hela cells human fetal brain tissue K562 cells Primary antibody: TA322435 (PDCD10 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

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  Immunohistochemistry of paraffin-embedded Human renal cancer tissue using TA322435 (PDCD10 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human renal cancer tissue using TA322435 (PDCD10 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Hela cells, human fetal brain tissue and K562 cells
  IHC: 15-50
  Positive control: Human renal cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: programmed cell death 10
• Database Link:
  NP_009148
  Entrez Gene 56426 MouseEntrez Gene 494345 RatEntrez Gene 11235 Human
  UniProt ID Q9BUL8
• Background: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25; and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations; which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants; encoding the same protein; have been identified.
• Synonyms: CCM3; TFAR15

Reference Data

• Protein Families: Druggable Genome