CDC37 Rabbit Polyclonal Antibody

CAT#: TA322445

Anti-CDC37 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: Hela cells Primary antibody: TA322445 (CDC37 Antibody) at dilution 1/100 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 90 seconds

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA322445 (CDC37 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA322445 (CDC37 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA322445 (CDC37 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA322445 (CDC37 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Hela cells
  IHC: 15-50
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 345-360 amino acids of human cell division cycle 37 homolog (S. cerevisiae)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 44 kDa
• Gene Name: cell division cycle 37
• Database Link:
  NP_008996
  Entrez Gene 12539 MouseEntrez Gene 114562 RatEntrez Gene 11140 Human
  UniProt ID Q16543
• Background: The protein encoded by this gene is highly similar to Cdc 37; a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4; CDK6; SRC; RAF-1; MOK; as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
• Synonyms: P50CDC37