Sumo 2 (SUMO2) Rabbit Polyclonal Antibody

CAT#: TA322452

Rabbit Polyclonal Anti-SUMO2/SUMO3/SUMO4 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse kidney tissue lysate
  IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 71-85 amino acids of human SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 12 kDa
• Gene Name: small ubiquitin-like modifier 2
• Database Link:
  NP_008868
  Entrez Gene 170930 MouseEntrez Gene 690244 RatEntrez Gene 6613 Human
  UniProt ID P61956
• Background: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Synonyms: HSMT3; Smt3A; SMT3B; SMT3H2; SUMO3

Reference Data

• Protein Families: Druggable Genome