RAB35 Rabbit Polyclonal Antibody

CAT#: TA322458

Anti-RAB35 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 121-135 amino acids of Human Ras-related protein Rab-35
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: RAB35, member RAS oncogene family
• Database Link:
  NP_006852
  Entrez Gene 77407 MouseEntrez Gene 288700 RatEntrez Gene 11021 Human
  UniProt ID Q15286
• Background: This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. Rab35 plays an important role in insulin-stimulated GLUT4 translocation in adipocytes.It is the target of TBC1D10A–C and that the intracellular accumulation of endosomal vesicles and impairs exosome secretion were occured when inhibition of Rab35 function.The surface of oligodendroglia in a GTP-dependent manner was localized Rab35; it increases the density of vesicles; and may have a function in docking or tethering.
• Synonyms: H-ray; RAB1C; RAY

Reference Data

• Protein Families: Druggable Genome