Peroxiredoxin 3 (PRDX3) Rabbit Polyclonal Antibody

CAT#: TA322472

Anti-PRDX3 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Hela and 293T cells
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 242-256 amino acids of Human peroxiredoxin 3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 28 kDa
• Gene Name: peroxiredoxin 3
• Database Link:
  NP_006784
  Entrez Gene 11757 MouseEntrez Gene 64371 RatEntrez Gene 10935 Human
  UniProt ID P30048
• Background: This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved; and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation; differentiation; and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.
• Synonyms: AOP-1; AOP1; HBC189; MER5; PRO1748; prx-III; SP-22

Reference Data

• Protein Families: Transcription Factors