Apoptosis inhibitor 5 (API5) Rabbit Polyclonal Antibody

CAT#: TA322479

Anti-API5 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T and hela cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 510-524 amino acids of Human apoptosis inhibitor 5
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 57 kDa
• Gene Name: apoptosis inhibitor 5
• Database Link:
  NP_006586
  Entrez Gene 11800 MouseEntrez Gene 362170 RatEntrez Gene 8539 Human
  UniProt ID Q9BZZ5
• Background: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with; and negatively regulates Acinus; a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
• Synonyms: AAC-11; AAC11

Reference Data

• Protein Families: Druggable Genome