Apoptosis inhibitor 5 (API5) Rabbit Polyclonal Antibody

CAT#: TA322480

Anti-API5 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 500-2000
WB positive control: 293T, A549 and Hela cells
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 510-524 amino acids of Human apoptosis inhibitor 5
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 57 kDa
Gene Name apoptosis inhibitor 5
Background This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with; and negatively regulates Acinus; a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms AAC-11; AAC11
Reference Data
Protein Families Druggable Genome

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