AGR2 Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommended Dilution | WB: 1000-5000 WB positive control: Mouse Large intestine tissue IHC: 10-50 Positive control: Human renal cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Full length fusion protein |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 20 kDa |
Gene Name | anterior gradient 2, protein disulphide isomerase family member |
Database Link | |
Background | Anterior gradient protein 2 homolog (AGR2) is a human protein originally discovered in Xenopus laevis; encoded for by the gene of the same name.In Xenopus AGR2 is an important role in cement gland differentiation; however in human cancer cell lines high levels of AGR2 correlate with reduction of the p53 response and AGR2 levels are elevated in the preneoplastic tissue Barrett's oesophagus. |
Synonyms | AG2; GOB-4; HAG-2; HEL-S-116; PDIA17; XAG-2 |
Reference Data | |
Protein Families | Secreted Protein |
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