Gastric Mucin (MUC6) Rabbit Polyclonal Antibody

CAT#: TA322537

Anti-MUC6 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1901-1915 amino acids of Human mucin 6, oligomeric mucus/gel-forming
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mucin 6, oligomeric mucus/gel-forming
• Database Link:
  NP_005952
  Entrez Gene 353328 MouseEntrez Gene 282586 RatEntrez Gene 4588 Human
  UniProt ID Q6W4X9
• Background: The MUC6 gene encodes gastric mucin; a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid; proteases; pathogenic microorganisms; and mechanical trauma in the gastrointestinal tract. May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis.
• Synonyms: MUC-6

Reference Data

• Protein Families: Druggable Genome