TRF2 (TERF2) Rabbit Polyclonal Antibody

CAT#: TA322571

Anti-TERF2 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322571 (TERF2 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322571 (TERF2 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm, Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 327-340 amino acids of human telomeric repeat binding factor 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: telomeric repeat binding factor 2
• Database Link:
  NP_005643
  Entrez Gene 21750 MouseEntrez Gene 361403 RatEntrez Gene 7014 Human
  UniProt ID Q15554
• Background: This gene encodes a telomere specific protein; TERF2; which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle; is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization; TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
• Synonyms: TRBF2; TRF2

Reference Data

• Protein Families: Transcription Factors