Smoothened (SMO) Rabbit Polyclonal Antibody

CAT#: TA322573

Anti-SMO Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 772-787 amino acids of human smoothened, frizzled family receptor
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: smoothened, frizzled class receptor
• Database Link:
  NP_005622
  Entrez Gene 25273 RatEntrez Gene 319757 MouseEntrez Gene 6608 Human
  UniProt ID Q99835
• Background: The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein; a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.
• Synonyms: FZD11; Gx; SMOH

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer