Cytokeratin 16 (KRT16) Rabbit Polyclonal Antibody

CAT#: TA322577

Anti-KRT16 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cells
  IHC: 50-200
  Positive control: Human colon cancer
  Predicted cell location: cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 195-212 amino acids of Human Keratin, type I cytoskeletal 16
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51 kDa
• Gene Name: keratin 16
• Database Link:
  NP_005548
  Entrez Gene 16666 MouseEntrez Gene 303530 RatEntrez Gene 3868 Human
  UniProt ID P08779
• Background: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues; including esophagus; tongue; and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita; non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
• Synonyms: CK16; FNEPPK; K1CP; K16; KRT16A; NEPPK; PC1