Laminin alpha 5 (LAMA5) Rabbit Polyclonal Antibody

CAT#: TA322581

Anti-LAMA5 Rabbit Polyclonal Antibody


USD 345.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 10-50
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm, Cell membrane
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 64-77 amino acids of Human laminin, alpha 5
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name laminin subunit alpha 5
Background Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular; the laminins; a family of heterotrimeric extracellular glycoproteins; affect tissue development and integrity in such diverse organs as the kidney; lung; skin; and nervous system. It is thought that laminins mediate the attachment; migration; and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha; beta; and gamma chains; with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene; but the full-length nature of one of them has not been determined.
Synonyms KIAA1907
Reference Data
Protein Families Druggable Genome
Protein Pathways ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.