Alanine Transaminase (GPT) Rabbit Polyclonal Antibody

CAT#: TA322630

Anti-GPT Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 10-50
Positive control: Human prostate cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 1-14 amino acids of Human glutamic-pyruvate transaminase (alanine aminotransferase)
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 54.6 kDa
Gene Name glutamic-pyruvate transaminase (alanine aminotransferase)
Background This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and; therefore; plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity; infection; alcohol; and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
Synonyms AAT1; ALT1; GPT1
Reference Data
Protein Families Druggable Genome
Protein Pathways Alanine, aspartate and glutamate metabolism, Metabolic pathways

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