FAT (FAT1) Rabbit Polyclonal Antibody

CAT#: TA322643

Anti-FAT1 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 50 kDa. Positive control: Recombinant protein. Recommended dilution: 1/ 2000-5000. (Gel: 10%SDS-PAGE Protein: 2 ug Primary antibody: 1/2000 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:2000-10000, WB: 1:2000-5000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide (KLH-coupled) derived from human FAT1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50 kDa
• Gene Name: FAT atypical cadherin 1
• Database Link:
  NP_005236
  Entrez Gene 2195 Human
  UniProt ID Q14517
• Background: This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.
• Synonyms: CDHF7; CDHR8; FAT; hFat1; ME5

Reference Data

• Protein Families: Druggable Genome, Transmembrane