NUMBL Rabbit Polyclonal Antibody
Other products for "NUMBL"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:500-2000 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to C terminal 280 amino acids of human numb homolog (Drosophila)-like |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 65 kDa |
Gene Name | NUMB like, endocytic adaptor protein |
Database Link | |
Background | Numb-like (Numbl or Nbl) binds Notch and is an intracellular modulator of Notch signaling pathway. Numbl contains a phosphotyrosine binding (PTB) domain that could bind the Y682 motif present in the cytoplasmic tail of APP. Deduced molecular weight of Numbl is 72 kDa. |
Synonyms | CAG3A; CTG3a; NBL; NUMB-R; NUMBLIKE; NUMBR; TNRC23 |
Reference Data | |
Protein Pathways | Notch signaling pathway |
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