Cathepsin H (CTSH) Rabbit Polyclonal Antibody

CAT#: TA322751

Anti-CTSH Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human liver cancer tissue
  IHC: 10-50
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 116-335 amino acids of human cathepsin H
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 37 kDa
• Gene Name: cathepsin H
• Database Link:
  NP_004381
  Entrez Gene 13036 MouseEntrez Gene 25425 RatEntrez Gene 1512 Human
  UniProt ID P09668
• Background: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains; both produced from a single protein precursor. The encoded protein; which belongs to the peptidase C1 protein family; can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors.
• Synonyms: ACC-4; ACC-5; ACC4; ACC5; CPSB

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome