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RUNX3 Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | WB: 500-2000 WB positive control: Raji cell lysate IHC: 25-100 Positive control: Human tonsil Predicted cell location: Nucleus |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 400-415 amino acids of human runt-related transcription factor 3 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 44 kDa |
| Gene Name | runt related transcription factor 3 |
| Database Link | |
| Background | This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Synonyms | AML2; CBFA3; PEBP2aC |
| Reference Data | |
| Protein Families | Transcription Factors |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.