Persephin (PSPN) Rabbit Polyclonal Antibody

CAT#: TA322783

Anti-PSPN Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 32-46 amino acids of human persephin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: persephin
• Database Link:
  NP_004149
  Entrez Gene 19197 MouseEntrez Gene 25525 RatEntrez Gene 5623 Human
  UniProt ID O60542
• Background: The protein encoded by this gene is a neurotrophic factor; belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury; toxin exposure; or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members; glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo.
• Synonyms: PSP

Reference Data

• Protein Families: Secreted Protein