FGF12 Rabbit Polyclonal Antibody

CAT#: TA322793

Anti-FGF12 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse brain tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20 kDa
• Gene Name: fibroblast growth factor 12
• Database Link:
  NP_004104
  Entrez Gene 14167 MouseEntrez Gene 170630 RatEntrez Gene 2257 Human
  UniProt ID P61328
• Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities; and are involved in a variety of biological processes; including embryonic development; cell growth; morphogenesis; tissue repair; tumor growth; and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members; but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells; this protein accumulated in the nucleus; but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [
• Synonyms: FGF12B; FHF1

Reference Data

• Protein Families: Secreted Protein
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton