COX8A Rabbit Polyclonal Antibody

CAT#: TA322804

Anti-COX8A Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322804 (COX8A Antibody) at dilution 1/12 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322804 (COX8A Antibody) at dilution 1/12, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA322804 (COX8A Antibody) at dilution 1/12 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA322804 (COX8A Antibody) at dilution 1/12, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 10-50
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cytochrome c oxidase subunit 8A
• Database Link:
  NP_004065
  Entrez Gene 12868 MouseEntrez Gene 171335 RatEntrez Gene 1351 Human
  UniProt ID P10176
• Background: The protein encoded by this gene is the terminal enzyme of the respiratory chain; coupling the transfer of electrons from cytochrome c to molecular oxygen; with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits; which perform the catalytic function; the eukaryotic enzyme contains nuclear-encoded smaller subunits; ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits.
• Synonyms: COX; COX8; COX8-2; COX8L; VIII; VIII-L

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease