IL18R1 Rabbit Polyclonal Antibody

CAT#: TA322816

Anti-IL18R1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: A549 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 351-541 amino acids of human interleukin 18 receptor 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 62 kDa
• Gene Name: interleukin 18 receptor 1
• Database Link:
  NP_003846
  Entrez Gene 16182 MouseEntrez Gene 301365 RatEntrez Gene 8809 Human
  UniProt ID Q13478
• Background: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18); and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family; including IL1R2; IL1R1; ILRL2 (IL-1Rrp2); and IL1RL1 (T1/ST2); form a gene cluster on chromosome 2q.?
• Synonyms: CD218a; CDw218a; IL-1Rrp; IL1RRP; IL18RA

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction