14-3-3 beta (YWHAB) Rabbit Polyclonal Antibody

CAT#: TA322854

Anti-YWHAB Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 30 μg Lane 1-2: Hela cells mouse kidney tissue Primary antibody: TA322854 (YWHAB Antibody) at dilution 1/550 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA322854 (YWHAB Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA322854 (YWHAB Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322854 (YWHAB Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322854 (YWHAB Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cells and mouse kidney tissue
  IHC: 25-100
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm, Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 72-87 amino acids of Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 28 kDa
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
• Database Link:
  NP_003395
  Entrez Gene 54401 MouseEntrez Gene 56011 RatEntrez Gene 7529 Human
  UniProt ID P31946
• Background: This gene encodes a protein belonging to the 14-3-3 family of proteins; members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases; suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants; which encode the same protein; have been identified for this gene.
• Synonyms: GW128; HEL-S-1; HS1; KCIP-1; YWHAA

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis