TIMP2 Rabbit Polyclonal Antibody

CAT#: TA322881

Anti-TIMP2 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 25-100
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 30-220 amino acids of human TIMP metallopeptidase inhibitor 2
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name TIMP metallopeptidase inhibitor 2
Background This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases; a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases; the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result; the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors; and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Synonyms CSC-21K; DDC8
Reference Data
Protein Families Druggable Genome, Secreted Protein

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